Blog
Insights on clinical trial matching, evidence-informed ranking, and AI in healthcare
Product Updates
Our monthly “What’s New” — the new pages, features, and matching improvements shipped each month.
September 1, 2026
August 2026 updates: four cancer drugs FDA-approved and captured the same cycle — daraxonrasib (the first RAS-targeted therapy for pancreatic cancer) and zanidatamab (now approved first-line for HER2-positive gastroesophageal cancer) among them — five new drug pages, our first non-cancer page (obesity/weight-loss trials), a dedicated HER2-positive breast cancer page, the ability to save or email your results, and sharper matching across a dozen specific cancers.
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August 1, 2026
July 2026 updates: six new drug pages — led by gedatolisib, which the FDA approved on July 14 for a large group of breast-cancer patients who previously had no targeted option — plus two new mechanism hubs (now 12 in all), a rebuilt results page that shows you why each trial matched and flags cross-cancer "basket" trials, smarter matching for heavily-pretreated and biomarker-specific patients, and stronger privacy protections.
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July 1, 2026
June 2026 updates: a new way to browse trials by mechanism (10 drug-class hubs — HER2 ADCs, TROP2 ADCs, KRAS inhibitors, CDK4/6, PARP, PSMA radioligand therapy, and the bispecific families — plus a /mechanisms catalog), 12 new drug pages (the catalog more than doubled), patient-focused ASCO 2026 coverage, a much faster wizard (the first step went from ~20 seconds to near-instant), and a batch of matching-accuracy fixes.
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June 1, 2026
May 2026 updates: 10 trial landscape pages for browse-before-you-search, 8 new drug pages (T-DXd, ivonescimab, cadonilimab, rilvegostomig, patritumab deruxtecan, daraxonrasib, ADI-PEG 20, tarlatamab), one-click prefill from cancer page to wizard, a faster treatment-history step that leads with line-of-therapy, and four ASCO 2026 patient previews.
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May 5, 2026
Five April improvements: per-trial detail pages with eligibility breakdowns, confidence tiers and surfacing reasons that explain why each match, faster searches (NPC dropped from 23 minutes to 13 minutes), wider coverage by expanding cancer-name synonyms, and a smoother wizard.
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March 30, 2026
Four improvements this month: search results now arrive in 5–15 minutes, non-treatment studies are filtered out more accurately, cross-cancer drug signals inform ranking, and remission status is recognized to prevent irrelevant matches.
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Guides & Insights
Plain-language explainers on how trial matching works — plus patient-focused research syntheses.
July 18, 2026
The best clinical trial for a patient increasingly doesn't have their cancer's name on it. Modern targeted therapies are tested in basket trials that enroll by a molecular target across many cancer types — so a search by cancer name walks right past them. This post explains how ClinTrialFinder matches by the molecule (on top of the usual diagnosis-based matching), how to recognize a basket trial in your results, and why the genuinely hard part isn't finding these trials but the tension between recall and precision.
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June 9, 2026 • Post-conference synthesis
ASCO 2026 (June 5–9, Chicago) closed today. Seven patient-relevant takeaways: (1) pan-RAS goes prime time with daraxonrasib in two Phase 3s at once (RASolve 301 NSCLC + RASolute 304 adjuvant PDAC); (2) ivonescimab keeps stacking 1L Phase 3 readouts (HARMONi-7) and moves into TNBC, biliary, and colorectal; (3) T-DXd + pertuzumab is the new HER2+ MBC frontline standard after DESTINY-Breast09 and the Dec 2025 FDA approval; (4) HER3-DXd (patritumab deruxtecan) reaches registrational Phase 3 in breast (HERTHENA-Breast03); (5) tarlatamab matures from salvage into maintenance, SubQ, and EP-NEC + brain expansion; (6) cadonilimab (PD-1/CTLA-4) and rilvegostomig (PD-1/TIGIT) bispecifics continue global Phase 3 expansion; (7) the personalized mRNA cancer vaccine V940 (intismeran) reaches Phase 3 in adjuvant resected NSCLC (INTerpath-002). 32 NCT citations.
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March 15, 2026
No more blank text boxes. ClinTrialFinder now walks you through clinical trial matching step by step—asking the right questions for your specific disease, showing relevant treatment options and biomarkers, and adapting the number of steps based on your condition. No medical knowledge required.
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March 6, 2026
You open a trial matching tool and see a text box: "Describe your condition." What do you write? This guide breaks down exactly what information helps—cancer type, stage, prior treatments, biomarkers—and what you can skip.
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March 3, 2026
Most clinical trial matching tools stop at relevance and eligibility screening. We tested a real cancer patient case and found that TrialGPT-only ranking would have shown the wrong trials first—including a diagnostic imaging study ranked #1. Evidence-informed ranking correctly identified novel therapies as the best options.
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