Multiple Myeloma Trial Landscape (May 2026)

Last updated: May 13, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

523
Recruiting
227
Phase 1
219
Phase 2
60
Phase 3
14
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

CAR-T cellular therapy
107
Cereblon / IMiD modulator
68
Bispecific antibody
67
Other / unclassified
22
Monoclonal antibody
21
Antibody-drug conjugate (ADC)
15
Other inhibitor
12
Proteasome inhibitor
12
Small-molecule inhibitor
5
CAR-NK cellular therapy
4
Vaccine (other)
4
Chemotherapy
3

Recently Updated Trials

NCTPhaseTitleMechanism
NCT069040661Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesPatient-specific neoantigen TCRs -- autologous T cell receptor (TCR) transduced T cells
NCT069340441A Study Evaluating the Pharmacokinetics, Safety, and Efficacy of Cevostamab in Chinese Participants With Relapsed or Refractory Multiple MyelomaFcRH5 -- bispecific antibody
NCT071166161, 2A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple MyelomaUnknown mechanism
NCT061525753MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)BCMA + SLAMF7 -- bispecific antibody (Elranatamab + Elotuzumab)
NCT069480842Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First RelapseCD38 + BCMA -- bispecific antibody (teclistamab) + monoclonal antibody (daratumumab)

Top Sponsors

SponsorRecruiting trials
Institute of Hematology & Blood Diseases Hospital, China23
Janssen Research & Development, LLC13
Memorial Sloan Kettering Cancer Center12
Regeneron Pharmaceuticals11
Washington University School of Medicine10

Geographic Distribution

Countries with the most active trial sites for multiple myeloma. A multi-site trial is counted once per country.

United States
227
China
158
France
54
Spain
49
Canada
41
Australia
39
United Kingdom
36
Germany
33
Japan
30
Italy
28

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Jul 2026NCT07479979Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple MyelomaXPO1 -- selective inhibitor of nuclear export (selinexor); Proteasome -- proteasome inhibitor (carfilzomib); CD38 -- monoclonal antibody (isatuximab)
Jul 2026NCT07221032FT836 CAR T-cell Therapy in Combination With Daratumumab in Patients With Relapsed and/or Refractory Multiple MyelomaNKG2D -- CAR-T + CD38 -- monoclonal antibody (daratumumab)
Jun 26, 2026NCT07463807Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After TreatmentBCMA + CD3 -- bispecific antibody (teclistamab); Cereblon modulator (pomalidomide); Proteasome inhibitor (carfilzomib)
Jun 1, 2026NCT07458659Clinical Study of BCMA-Targeted CAR T-Cell Injection in the Treatment of Patients With Relapsed/Refractory Multiple MyelomaBCMA -- CAR-T cell therapy
Jun 1, 2026NCT07407010BCMA/CD3 Bispecific Antibody as Bridging Therapy Before CAR-T Cell Infusion in RRMMBCMA + CD3 -- bispecific antibody
Jun 1, 2026NCT04579523²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple MyelomaCD38 -- radioimmunotherapy (211At-OKT10-B10)
Jun 1, 2026NCT07558915A Study to Evaluate RO7851624 in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)CD38 -- antibody-drug conjugate (ADC)
May 31, 2026NCT07200089Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)IL-7 receptor -- cytokine receptor agonist (NT-I7)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.