Pancreatic Cancer Trial Landscape (September 2026)

Last updated: Sep 9, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

668
Recruiting
231
Phase 1
316
Phase 2
64
Phase 3
9
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Chemotherapy
83
Checkpoint inhibitor
51
Other / unclassified
51
Antibody-drug conjugate (ADC)
23
Monoclonal antibody
18
Bispecific antibody
17
Other inhibitor
17
CAR-T cellular therapy
16
Small-molecule inhibitor
16
Vaccine (other)
11
mRNA / neoantigen vaccine
8
Radioligand / radiopharmaceutical
7

Recently Updated Trials

NCTPhaseTitleMechanism
NCT07360119Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic TumorsUnknown mechanism
NCT036086311, 2iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D MutationKRAS G12D -- siRNA delivered by mesenchymal stromal cell-derived exosomes
NCT064004721A Study of Sofe-M in Participants With Selected Advanced Solid TumorsUnknown mechanism
NCT040056901Targeted Pathway Inhibition in Patients With Pancreatic CancerMEK -- MEK inhibitor (cobimetinib); PARP -- PARP inhibitors (olaparib, saruparib); PLK1 -- PLK1 inhibitor (onvansertib); WEE1 -- WEE1 inhibitor (azenosertib)
NCT048583342APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 MutationPARP inhibition (Olaparib)

Top Sponsors

SponsorRecruiting trials
Fudan University19
Tianjin Medical University Cancer Institute and Hospital14
Ruijin Hospital13
Zhejiang University12
West China Hospital9

Geographic Distribution

Countries/regions with the most active trial sites for pancreatic cancer. A multi-site trial is counted once per country/region.

United States
229
China
216
France
50
Spain
33
Canada
32
Italy
31
South Korea
27
Japan
24
United Kingdom
21
Netherlands
19

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Dec 16, 2026NCT0760862764Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic CancerPSCA -- radiolabeled antibody fragment for imaging (radioconjugate)
Nov 1, 2026NCT07587827Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic CancerNeoantigens + CTLA-4 -- personalized DNA neoantigen vaccine combined with immune checkpoint blockade (anti-CTLA4 antibody)
Nov 2026NCT07738939IKS04 Regimen in Advanced Solid Tumors That Express CA242CA242 -- antibody-drug conjugate (ADC)
Sep 30, 2026NCT07394205Clinical Study of CBG131 CAR-T Cell Injection for the Treatment of CLDN18.2-Positive Advanced Gastric and Pancreatic CancerCLDN18.2 -- CAR-T cell therapy
Sep 15, 2026NCT07645651Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic CancerCDK7 -- kinase inhibitor (small molecule)
Sep 10, 2026NCT07802184GnP Combined With SHR-1701 and Apatinib as First-Line Treatment for Locally Advanced or Metastatic PDACPD-L1 + TGF-β receptor -- bispecific antibody (SHR-1701) + VEGFR2 -- tyrosine kinase inhibitor (Apatinib)
Sep 8, 2026NCT07619521Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a, for Advanced Pancreatic Ductal AdenocarcinomaMEK1/2 + HER2 -- MEK inhibitor + antibody-drug conjugate (ADC)
Sep 2026NCT07698613EGFR Targeted Photoimmunotherapy With ASP-1929 for Locally Advanced Pancreatic CancerEGFR -- antibody-photoabsorber conjugate (photoimmunotherapy)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.