Pancreatic Cancer Trial Landscape (August 2026)

Last updated: Aug 20, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

665
Recruiting
233
Phase 1
316
Phase 2
63
Phase 3
9
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Chemotherapy
85
Other / unclassified
52
Checkpoint inhibitor
51
Antibody-drug conjugate (ADC)
21
Monoclonal antibody
18
Bispecific antibody
17
CAR-T cellular therapy
16
Small-molecule inhibitor
16
Other inhibitor
16
Vaccine (other)
11
mRNA / neoantigen vaccine
8
Radioligand / radiopharmaceutical
7

Recently Updated Trials

NCTPhaseTitleMechanism
NCT059192381Padeliporfin VTP Treatment for Unresectable Pancreatic AdenocarcinomaUnknown mechanism
NCT071753891, 2JDB153 Combined With Serplulimab for Pancreatic Cancer After Standard Treatment FailureUnknown mechanism
NCT072142981, 2Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal AdenocarcinomaComplement C3 -- complement inhibitor (pegcetacoplan) combined with chemotherapy
NCT034540351Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid TumorsERK + CDK4/6 -- kinase inhibition (ERK inhibitor + CDK4/6 inhibitor)
NCT011741212Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic CancerTumor infiltrating lymphocytes (TILs) plus PD-1 blockade -- adoptive cell therapy plus immune checkpoint inhibitor

Top Sponsors

SponsorRecruiting trials
Fudan University21
Ruijin Hospital13
Zhejiang University12
Tianjin Medical University Cancer Institute and Hospital11
West China Hospital8

Geographic Distribution

Countries/regions with the most active trial sites for pancreatic cancer. A multi-site trial is counted once per country/region.

United States
226
China
212
France
50
Spain
32
Italy
32
Canada
31
South Korea
26
Japan
23
United Kingdom
20
Netherlands
18

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Dec 16, 2026NCT0760862764Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic CancerPSCA -- radiolabeled antibody fragment for imaging (radioconjugate)
Nov 1, 2026NCT07587827Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic CancerNeoantigens + CTLA-4 -- personalized DNA neoantigen vaccine combined with immune checkpoint blockade (anti-CTLA4 antibody)
Nov 2026NCT07738939IKS04 Regimen in Advanced Solid Tumors That Express CA242CA242 -- antibody-drug conjugate (ADC)
Oct 1, 2026NCT07645651Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic CancerCDK7 -- kinase inhibitor (small molecule)
Sep 30, 2026NCT07394205Clinical Study of CBG131 CAR-T Cell Injection for the Treatment of CLDN18.2-Positive Advanced Gastric and Pancreatic CancerCLDN18.2 -- CAR-T cell therapy
Sep 8, 2026NCT07619521Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a, for Advanced Pancreatic Ductal AdenocarcinomaMEK1/2 + HER2 -- MEK inhibitor + antibody-drug conjugate (ADC)
Sep 2026NCT07698613EGFR Targeted Photoimmunotherapy With ASP-1929 for Locally Advanced Pancreatic CancerEGFR -- antibody-photoabsorber conjugate (photoimmunotherapy)
Sep 2026NCT07756281First in Human Study of SNV1521 With a RAS Inhibitor for People With Advanced Pancreatic CancerRAS -- inhibitor (small molecule)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.