Pancreatic Cancer Trial Landscape (June 2026)

Last updated: Jun 27, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

659
Recruiting
232
Phase 1
309
Phase 2
61
Phase 3
9
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Chemotherapy
89
Other / unclassified
55
Checkpoint inhibitor
51
CAR-T cellular therapy
18
Antibody-drug conjugate (ADC)
18
Small-molecule inhibitor
17
Monoclonal antibody
16
Bispecific antibody
15
Other inhibitor
13
Vaccine (other)
12
mRNA / neoantigen vaccine
8
Radioligand / radiopharmaceutical
6

Recently Updated Trials

NCTPhaseTitleMechanism
NCT072625673Phase III Study to Compare GFH375 and Chemotherapy in Patients With KRAS G12D-Mutant Metastatic Pancreatic CancerKRAS G12D -- targeted inhibitor
NCT07605819Pancreatic Cancer Screening Using the Enzeavour Assay in JapanUnknown mechanism
NCT076309611Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid TumorsUnknown mechanism
NCT076445592A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic CancerKRAS G12D -- inhibitor (small molecule)
NCT076713391A Study of ELI-002 7P, With or Without Tislelizumab, in People With Pancreatic CancerTumor antigens -- peptide vaccine (ELI-002 7P) + PD-1 -- immune checkpoint inhibitor (Tislelizumab)

Top Sponsors

SponsorRecruiting trials
Fudan University21
Zhejiang University13
Tianjin Medical University Cancer Institute and Hospital12
Ruijin Hospital12
National Cancer Institute (NCI)8

Geographic Distribution

Countries/regions with the most active trial sites for pancreatic cancer. A multi-site trial is counted once per country/region.

United States
228
China
213
France
51
Spain
31
Italy
31
Canada
29
South Korea
25
Japan
23
United Kingdom
19
Netherlands
18

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Dec 16, 2026NCT0760862764Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic CancerPSCA -- radiolabeled antibody fragment for imaging (radioconjugate)
Nov 1, 2026NCT07587827Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic CancerNeoantigens + CTLA-4 -- personalized DNA neoantigen vaccine combined with immune checkpoint blockade (anti-CTLA4 antibody)
Sep 30, 2026NCT07394205Clinical Study of CBG131 CAR-T Cell Injection for the Treatment of CLDN18.2-Positive Advanced Gastric and Pancreatic CancerCLDN18.2 -- CAR-T cell therapy
Sep 8, 2026NCT07619521Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a, for Advanced Pancreatic Ductal AdenocarcinomaMEK1/2 + HER2 -- MEK inhibitor + antibody-drug conjugate (ADC)
Aug 2026NCT07539155Intratumoral MMR Vaccine Injection in Borderline Resectable/Unresectable Pancreatic CancerMeasles, mumps, rubella virus antigens -- intratumoral vaccine
Jul 1, 2026NCT07645651Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic CancerCDK7 -- kinase inhibitor (small molecule)
Jul 2026NCT07153289CD318-targeted CAR-T Cell Therapy in Patients With Pancreatic Cancer (ResCPa)CD318 -- CAR-T cell therapy targeting CD318
Jul 2026NCT07594067TCR1188-ABC Cells in KRAS-mutated CancersKRAS mutant peptides -- T cell receptor (TCR) engineered T cells

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.