Pancreatic Cancer Trial Landscape (October 2026)

Last updated: Oct 4, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

680
Recruiting
228
Phase 1
320
Phase 2
64
Phase 3
9
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Chemotherapy
83
Other / unclassified
52
Checkpoint inhibitor
51
Antibody-drug conjugate (ADC)
23
Bispecific antibody
19
Small-molecule inhibitor
18
Monoclonal antibody
18
Other inhibitor
17
CAR-T cellular therapy
16
Vaccine (other)
11
mRNA / neoantigen vaccine
8
Radioligand / radiopharmaceutical
6

Recently Updated Trials

NCTPhaseTitleMechanism
NCT072268562BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic AdenocarcinomaUnknown mechanism
NCT074914453Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic AdenocarcinomaKRAS(ON) -- RAS inhibitor (daraxonrasib) combined with chemotherapy
NCT068856971Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaMesothelin -- chimeric antigen receptor T cell therapy (CAR T)
NCT011741212Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic CancerTumor infiltrating lymphocytes (TILs) plus PD-1 blockade -- adoptive cell therapy plus immune checkpoint inhibitor
NCT074903012, 3A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinomac-Met -- antibody-drug conjugate (telisotuzumab adizutecan) + chemotherapy

Top Sponsors

SponsorRecruiting trials
Fudan University20
Tianjin Medical University Cancer Institute and Hospital17
Ruijin Hospital13
Zhejiang University12
West China Hospital8

Geographic Distribution

Countries/regions with the most active trial sites for pancreatic cancer. A multi-site trial is counted once per country/region.

United States
231
China
222
France
49
Spain
35
Italy
32
Canada
30
South Korea
28
Japan
25
United Kingdom
23
Australia
19

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Jun 1, 2027NCT07619521Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal AdenocarcinomaMEK1/2 + HER2 -- MEK inhibitor + antibody-drug conjugate (ADC)
Dec 16, 2026NCT0760862764Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic CancerPSCA -- radiolabeled antibody fragment for imaging (radioconjugate)
Dec 2026NCT07829185Modified FOLFIRINOX and Pentamidine in Advanced and Metastatic Pancreatic CancerMultiple DNA synthesis and topoisomerase enzymes -- multi-agent chemotherapy (antimetabolite and topoisomerase inhibitor)
Nov 1, 2026NCT07587827Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic CancerNeoantigens + CTLA-4 -- personalized DNA neoantigen vaccine combined with immune checkpoint blockade (anti-CTLA4 antibody)
Nov 2026NCT07738939IKS04 Regimen in Advanced Solid Tumors That Express CA242CA242 -- antibody-drug conjugate (ADC)
Oct 15, 2026NCT07645651Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic CancerCDK7 -- kinase inhibitor (small molecule)
Oct 15, 2026NCT07828236PHASE 1 TRIAL OF Lm-LLO-TT AND GEMCITABINE IN UNRESECTABLE PANCREATIC DUCTAL ADENOCARCINOMAListeria monocytogenes expressing Listeriolysin O and Tetanus Toxin fragment -- bacterial vector vaccine (biological)
Oct 10, 2026NCT07627191GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular CancerGLP-1 receptor -- receptor agonist (GLP-1 RA)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.