Pancreatic Cancer Trial Landscape (June 2026)

Last updated: Jun 9, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

646
Recruiting
228
Phase 1
307
Phase 2
61
Phase 3
9
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Chemotherapy
90
Other / unclassified
56
Checkpoint inhibitor
51
CAR-T cellular therapy
18
Antibody-drug conjugate (ADC)
18
Small-molecule inhibitor
17
Monoclonal antibody
16
Bispecific antibody
15
Vaccine (other)
11
Other inhibitor
10
mRNA / neoantigen vaccine
8
Radioligand / radiopharmaceutical
5

Recently Updated Trials

NCTPhaseTitleMechanism
NCT067906022Cemiplimab Plus Gemcitabine in Patients With Metastatic Pancreatic AdenocarcinomaPD-1 -- immune checkpoint inhibitor (monoclonal antibody)
NCT071454501, 2Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDACKRAS G12V/D -- TCR-engineered T cells
NCT061581391Autologous CAR-T Cells Targeting B7-H3 in PDACB7-H3 -- CAR-T cell therapy
NCT072142981, 2Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal AdenocarcinomaComplement C3 -- complement inhibitor (pegcetacoplan) combined with chemotherapy
NCT072774131A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsMTAP-deletion -- unknown mechanism targeted therapy

Top Sponsors

SponsorRecruiting trials
Fudan University21
Zhejiang University13
Tianjin Medical University Cancer Institute and Hospital12
Ruijin Hospital11
M.D. Anderson Cancer Center9

Geographic Distribution

Countries/regions with the most active trial sites for pancreatic cancer. A multi-site trial is counted once per country/region.

United States
224
China
209
France
50
Spain
30
Italy
29
Canada
28
South Korea
24
United Kingdom
18
Netherlands
18
Japan
18

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Dec 16, 2026NCT0760862764Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic CancerPSCA -- radiolabeled antibody fragment for imaging (radioconjugate)
Nov 1, 2026NCT07587827Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic CancerNeoantigens + CTLA-4 -- personalized DNA neoantigen vaccine combined with immune checkpoint blockade (anti-CTLA4 antibody)
Sep 30, 2026NCT07394205Clinical Study of CBG131 CAR-T Cell Injection for the Treatment of CLDN18.2-Positive Advanced Gastric and Pancreatic CancerCLDN18.2 -- CAR-T cell therapy
Sep 8, 2026NCT07619521Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a, for Advanced Pancreatic Ductal AdenocarcinomaMEK1/2 + HER2 -- MEK inhibitor + antibody-drug conjugate (ADC)
Jul 1, 2026NCT07377526Phase 1/2 Study TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic CancerTROP2-targeted CAR NK cells with IL-15 expression and TGFBR2 knockout + HIF-2α inhibition (Belzutifan)
Jul 2026NCT07153289CD318-targeted CAR-T Cell Therapy in Patients With Pancreatic Cancer (ResCPa)CD318 -- CAR-T cell therapy targeting CD318
Jul 2026NCT07594067TCR1188-ABC Cells in KRAS-mutated CancersKRAS mutant peptides -- T cell receptor (TCR) engineered T cells
Jun 30, 2026NCT07627191GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular CancerGLP-1 receptor -- receptor agonist (GLP-1 RA)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.