Clinical Trials by Drug Mechanism / Class

Browse recruiting clinical trials by therapeutic mechanism class. Mechanism hubs are useful when your oncologist mentioned a drug class by name (for example, "BCMA bispecific" or "PSMA radioligand") and you want to see all the recruiting options in that class side-by-side. For most patients, browsing by disease is the right starting point.

Data from ClinicalTrials.gov

Multiple Myeloma — Bispecific T-Cell Engagers

Prostate Cancer — Targeted Radiation

Cross-Cancer — HER2 + TROP2 Antibody-Drug Conjugates

Cross-Cancer — CLDN18.2 Targeted Therapies

Cross-Cancer — B7-H3 (CD276) Targeted Therapies

Cross-Cancer — Bispecific Checkpoint Inhibitors

Cross-Cancer — KRAS Inhibitors

Cross-Cancer — KRAS-Mutant & Neoantigen Cancer Vaccines

HR+/HER2- Breast Cancer Backbone — CDK4/6 Inhibitors

Cross-Cancer DNA Damage Response — PARP Inhibitors

Cross-Cancer Anti-Angiogenic — Multikinase Inhibitors (VEGFR / FGFR / RET / KIT / MET / PDGFR)

Coming Soon — Planned Mechanism Hubs

FRα Antibody-Drug Conjugates

Hub coming soon

DLL3-Targeted Therapies

Hub coming soon

Don't know which mechanism class fits your situation?

Use ClinTrialFinder's AI-powered matching to search by disease, biomarker, or prior treatment history — no need to know the drug class up front.

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Browsing by Disease or Drug Instead

If you already know the cancer type you're researching, start with the disease-specific trial pages. Browse trials by disease →

If you know the specific drug name your oncologist mentioned, the drug-anchored pages cover each drug in depth. Browse trials by drug →