Breast Cancer Trial Landscape (September 2026)

Last updated: Sep 9, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

2,307
Recruiting
327
Phase 1
824
Phase 2
264
Phase 3
65
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Antibody-drug conjugate (ADC)
180
Chemotherapy
127
Hormonal / nuclear-receptor therapy
124
Checkpoint inhibitor
122
Other / unclassified
116
Other inhibitor
73
Kinase inhibitor (other)
55
Monoclonal antibody
44
Tyrosine kinase inhibitor (TKI)
40
Bispecific antibody
36
CAR-T cellular therapy
16
Vaccine (other)
15

Recently Updated Trials

NCTPhaseTitleMechanism
NCT073004751Personalized Cancer Vaccine (PCV) Strategy in Triple Negative Breast Cancer PatientsPD-1 + chemotherapy agents -- immune checkpoint inhibitor + chemotherapy
NCT072879171, 2Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid TumorsPolyamine transport inhibitor (AMXT 1501) + ornithine decarboxylase inhibitor (DFMO) + estrogen receptor antagonist (fulvestrant) + AKT inhibitor (capivasertib) + PD-1 -- immune checkpoint inhibitor (pembrolizumab)
NCT064305411Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence5-HT2A receptor agonist -- psychedelic agent (psychedelic drug)
NCT063778523The CDK4/6 Inhibitor Dosing Knowledge (CDK) StudyCDK4/6 -- cyclin-dependent kinase 4/6 inhibitors
NCT058270813Phase IIIb Study of Ribociclib + ET in Early Breast CancerCDK4/6 -- cyclin-dependent kinase 4/6 inhibitor

Top Sponsors

SponsorRecruiting trials
Fudan University107
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University40
Memorial Sloan Kettering Cancer Center36
Cancer Institute and Hospital, Chinese Academy of Medical Sciences29
The First Affiliated Hospital with Nanjing Medical University27

Geographic Distribution

Countries/regions with the most active trial sites for breast cancer. A multi-site trial is counted once per country/region.

United States
726
China
607
France
161
Italy
124
Spain
122
Canada
102
South Korea
96
Germany
92
Australia
75
United Kingdom
68

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Jun 1, 2027NCT04430595Multi-4SCAR-T Therapy Targeting Breast CancerHer2 + GD2 + CD44v6 -- chimeric antigen receptor T cells (CAR-T)
Jun 2027NCT04861077Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI)Tumor hypoxia -- 18F-fluoromisonidazole PET with MRI (diagnostic imaging)
Dec 2026NCT07785856Study of Trastuzumab Deruxtecan (T-DXd) in Combination With a RAGE Inhibitor in Patients With T-DXd-Resistant HER2-Positive or HER2-Low Metastatic Breast CancerHER2 + RAGE -- antibody-drug conjugate (T-DXd) combined with RAGE inhibitor
Nov 2026NCT07730125Gene-edited T Regulatory Cells (CRG-150) for the Treatment of Relapsed/Refractory MalignanciesRegulatory T cells -- gene-edited cell therapy
Oct 30, 2026NCT07272642A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.LRRC15 -- radiolabeled monoclonal antibody (radioimmunotherapy)
Oct 1, 2026NCT07300475Personalized Cancer Vaccine (PCV) Strategy in Triple Negative Breast Cancer PatientsPD-1 + chemotherapy agents -- immune checkpoint inhibitor + chemotherapy
Oct 1, 2026NCT07553390Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast CancersTGFBR2 -- knockout; TROP2 -- chimeric antigen receptor (CAR) NK cells; HER2 -- antibody-drug conjugate (trastuzumab deruxtecan)
Oct 2026NCT07581314Oral Zn-Telomir Monotherapy in Patients With Advanced or Metastatic Triple-Negative Breast Cancer (TNBC)Telomerase -- inhibitor (Zn-Telomir)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.