Breast Cancer Trial Landscape (May 2026)

Last updated: May 28, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

2,276
Recruiting
333
Phase 1
792
Phase 2
263
Phase 3
64
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

Looking for breast cancer trials matched to your specific case?

Biomarkers, stage, prior treatments — get a ranked shortlist in minutes.

Find My Matches →

Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Antibody-drug conjugate (ADC)
169
Chemotherapy
128
Checkpoint inhibitor
128
Hormonal / nuclear-receptor therapy
121
Other / unclassified
116
Other inhibitor
69
Kinase inhibitor (other)
53
Monoclonal antibody
42
Bispecific antibody
37
Tyrosine kinase inhibitor (TKI)
36
CAR-T cellular therapy
16
Small-molecule inhibitor
15

Recently Updated Trials

NCTPhaseTitleMechanism
NCT063243571, 2Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has SpreadHER2 -- tyrosine kinase inhibitor and antibody-drug conjugates
NCT024226412Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal MetastasisDihydrofolate reductase -- high-dose methotrexate (antimetabolite chemotherapy)
NCT066310921, 2Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast CancerTumor neoantigens -- personalized DNA vaccine
NCT07426913Cardiovascular Health Education Via Virtual Reality for Breast Cancer Survivors Receiving Anthracyclines or TrastuzumabUnknown mechanism
NCT072372563Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant RibociclibCDK4/6 -- kinase inhibitor (CDK4/6 inhibitor)

Top Sponsors

SponsorRecruiting trials
Fudan University106
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University39
Memorial Sloan Kettering Cancer Center34
Cancer Institute and Hospital, Chinese Academy of Medical Sciences29
The First Affiliated Hospital with Nanjing Medical University28

Geographic Distribution

Countries/regions with the most active trial sites for breast cancer. A multi-site trial is counted once per country/region.

United States
715
China
604
France
168
Spain
127
Italy
122
Canada
104
South Korea
95
Germany
91
United Kingdom
73
Australia
73

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Oct 1, 2026NCT07553390Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast CancersTGFBR2 -- knockout; TROP2 -- chimeric antigen receptor (CAR) NK cells; HER2 -- antibody-drug conjugate (trastuzumab deruxtecan)
Sep 2026NCT07545122A Phase 1a/1b, First-Time-in-Human Study of CT-202, a Nectin-4 Directed Bispecific Antibody, in Participants With Recurring Triple Negative Breast, Colorectal, Urothelial CancersNectin-4 -- bispecific antibody (CT-202)
Jul 3, 2026NCT07601620A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of HLX319 vs. EU-Phesgo® in the Neoadjuvant Therapy of HER2-Positive Early or Locally Advanced Breast CancerHER2 -- monoclonal antibody (HLX319, biosimilar to Phesgo)
Jul 1, 2026NCT07494448Phase Ib/II Study of Zanidatamab Plus Tucatinib and Chemotherapy in HER2-Positive Advanced Breast CancerHER2 -- bispecific antibody plus HER2 tyrosine kinase inhibitor
Jul 2026NCT07136428Asciminib in HER2+ Breast Cancer Brain MetastasesBCR-ABL allosteric site -- allosteric inhibitor + HER2 -- monoclonal antibody
Jun 30, 2026NCT07300475Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer PatientsPD-1 + chemotherapy agents -- immune checkpoint inhibitor + chemotherapy
Jun 15, 2026NCT06148038CBD for Breast Cancer Primary TumorsCannabinoid receptor -- cannabinoid receptor agonist (CBD)
Jun 2026NCT06949410HER2 Vaccine for Locally Advanced Breast CancerHER2 -- therapeutic vaccine

You've seen the breast cancer landscape. Now find the trials that fit your case.

Enter biomarkers, stage, and prior treatments — get ranked matches with eligibility breakdown in minutes.

Find My Matches →

Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.