Prostate Cancer Trial Landscape (August 2026)

Last updated: Aug 26, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

1,069
Recruiting
247
Phase 1
386
Phase 2
112
Phase 3
20
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

Looking for prostate cancer trials matched to your specific case?

Biomarkers, stage, prior treatments — get a ranked shortlist in minutes.

Find My Matches →

Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Hormonal / nuclear-receptor therapy
118
Other / unclassified
87
Radioligand / radiopharmaceutical
74
Other inhibitor
26
Chemotherapy
21
CAR-T cellular therapy
14
Antibody-drug conjugate (ADC)
14
Checkpoint inhibitor
12
Small-molecule inhibitor
9
Bispecific antibody
7
Kinase inhibitor (other)
5
Monoclonal antibody
4

Recently Updated Trials

NCTPhaseTitleMechanism
NCT060247723Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate CancerUnknown mechanism
NCT071644433A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)Unknown mechanism
NCT060228222Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO TrialUnknown mechanism
NCT060856641, 2A Pilot Presurgical Trial of REGN5678 (Anti-PSMA x CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical ProstatectomyProstate-specific membrane antigen (PSMA) + CD28 -- bispecific antibody
NCT073166861Phase I Study of Docetaxel and 177-Lutetium-PSMA-I&T in First-Line Treatment for Patients With Metastatic Castration-Resistant Prostate AdenocarcinomaProstate-Specific Membrane Antigen (PSMA) -- targeted radioligand therapy with 177Lu-PSMA-I&T combined with docetaxel chemotherapy

Top Sponsors

SponsorRecruiting trials
University Health Network, Toronto21
M.D. Anderson Cancer Center16
Memorial Sloan Kettering Cancer Center15
Mayo Clinic15
National Cancer Institute (NCI)14

Geographic Distribution

Countries/regions with the most active trial sites for prostate cancer. A multi-site trial is counted once per country/region.

United States
499
China
182
Canada
113
France
69
United Kingdom
63
Australia
62
Spain
54
Germany
52
Italy
48
South Korea
39

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Mar 2028NCT05896371A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical TherapyProstate-specific membrane antigen (PSMA) -- radioligand therapy with lutetium-177 labeled PSMA ligand
Nov 30, 2026NCT07756593Sipuleucel-T (Sip-T) in Combination With N-803 in Metastatic Androgen Pathway Modulation Resistant (mAPMR) Prostate CancerProstate cancer antigens -- autologous cellular immunotherapy (Sipuleucel-T) + IL-15 superagonist -- immune activation (N-803)
Nov 2026NCT07730125Gene-edited T Regulatory Cells (CRG-150) for the Treatment of Relapsed/Refractory MalignanciesRegulatory T cells -- gene-edited cell therapy
Oct 2026NCT07674771Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy DeliveryPSMA -- radiolabeled ligand for PET imaging and targeted radiotherapy
Aug 31, 2026NCT07783282A Study to Learn How Enzalutamide, Apalutamide and Bicalutamide Affect the Way Fezolinetant is Processed in Men With Prostate CancerAndrogen receptor -- androgen receptor antagonists (enzalutamide, apalutamide, bicalutamide) and neurokinin 3 receptor -- small molecule antagonist (fezolinetant)
Aug 30, 2026NCT07667400Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate CancerCXCR1/2 -- small molecule antagonist (chemokine receptor inhibitor)
Aug 17, 2026NCT07746713A Study of JNJ-98768111 in Participants With Advanced Prostate CancerPARP1/2 -- PARP inhibitor
Aug 10, 2026NCT07543055A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has SpreadPSCA -- chimeric antigen receptor T-cell therapy (CAR-T)

You've seen the prostate cancer landscape. Now find the trials that fit your case.

Enter biomarkers, stage, and prior treatments — get ranked matches with eligibility breakdown in minutes.

Find My Matches →

Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.