Prostate Cancer Trial Landscape (July 2026)

Last updated: Jul 12, 2026 · Built by a patient who got tired of scrolling ClinicalTrials.gov

Overview

1,056
Recruiting
242
Phase 1
379
Phase 2
110
Phase 3
20
Phase 4

Active interventional trials with status RECRUITING or NOT_YET_RECRUITING. A multi-phase trial (e.g. 1/2) is counted in each of its phases.

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Mechanism Breakdown

Recruiting trials grouped by drug class. Trials with unclassifiable or non-therapeutic interventions are excluded from this view.

Hormonal / nuclear-receptor therapy
114
Other / unclassified
86
Radioligand / radiopharmaceutical
74
Chemotherapy
22
Other inhibitor
21
CAR-T cellular therapy
15
Antibody-drug conjugate (ADC)
15
Checkpoint inhibitor
13
Small-molecule inhibitor
9
Bispecific antibody
7
Monoclonal antibody
5
Kinase inhibitor (other)
5

Recently Updated Trials

NCTPhaseTitleMechanism
NCT07142967Trial Evaluating the Safety and Efficacy Of MR-Linac-Guided Radiotherapy as Salvage Treatment After External Beam Radiotherapy Recurrence (TUMORNATOR II)Androgen receptor -- antagonist (ADT); Unknown mechanism (MR-Linac-guided radiotherapy)
NCT056166502Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate TumorUnknown mechanism
NCT058006651A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate CancerUnknown mechanism
NCT069106571IDOV-Immune for Advanced Solid TumorsOncolytic vaccinia virus -- oncolytic virus therapy (IDOV-Immune)
NCT070483141, 2Stem Cells for Erectile Dysfunction Post RALPUnknown mechanism

Top Sponsors

SponsorRecruiting trials
University Health Network, Toronto20
Mayo Clinic16
National Cancer Institute (NCI)15
Memorial Sloan Kettering Cancer Center15
M.D. Anderson Cancer Center15

Geographic Distribution

Countries/regions with the most active trial sites for prostate cancer. A multi-site trial is counted once per country/region.

United States
499
China
184
Canada
110
France
68
Australia
62
United Kingdom
61
Spain
54
Germany
54
Italy
49
South Korea
41

Emerging Classes

Phase-1 trials whose listed start date falls within the last 12 months — the leading edge of the field.

StartNCTTitleMechanism
Mar 2028NCT05896371A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical TherapyProstate-specific membrane antigen (PSMA) -- radioligand therapy with lutetium-177 labeled PSMA ligand
Aug 1, 2026NCT07682649Escalating Cycle 1 Dose of Lu-177-PSMA-617 for the Treatment of Metastatic Castration Resistant Prostate CancerProstate-specific membrane antigen (PSMA) -- radioligand therapy (radiolabeled small molecule)
Jul 15, 2026NCT07667400Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate CancerCXCR1/2 -- small molecule antagonist (chemokine receptor inhibitor)
Jul 15, 2026NCT07674771Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy DeliveryPSMA -- radiolabeled ligand for PET imaging and targeted radiotherapy
Jul 7, 2026NCT07543055A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has SpreadPSCA -- chimeric antigen receptor T-cell therapy (CAR-T)
Jul 1, 2026NCT06906471A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NSPSMA -- fluorescent histopathology agent
Jul 2026NCT07581184A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate CancerPSMA -- targeted alpha-particle radioligand therapy
Jul 2026NCT07683013Safety, Tolerability, and Efficacy of CP-PCA07 in Combination With Enzalutamide in Patients With Castration-Resistant Prostate CancerAndrogen receptor -- antagonist (AR inhibitor)

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Source: ClinicalTrials.gov, synced daily. Aggregated by ClinTrialFinder.